All included patients will receive study medication for one-year´s usage and take one tablet once a day, every day for up to three years. Tablets should be swallowed whole with water, preferably with a meal. It is very important that the tablets are taken every day. If you forget to take a tablet, do not take additional tablets to catch-up. If you are going to receive a surgical or dental treatment, please inform that you are participating in the ASAC trial and may be on ASA 160 mg. You can in case of treatment stop taking the tablets for 5 days. Please register how many days the tablets are not taken.